downregulation of mmp2 and bcl-2 in adipose derived stem cells (ascs) following transfection with ip-10 gene

Downregulation of MMP2 and Bcl-2 in Adipose Derived Stem Cells (ASCs) following Transfection with IP-10 Gene

BACKGROUND Mesenchymal Stem Cells (MSCs) are recently introduced as novel immunological gene carriers for treatment of cancer. It is believed that balance between the expression of angiogenic and anti-angiogenic factors, such as SDF-1 and IP-10, may regulate neovascularization within the tumor. METHODS In this study, we compared the expression of important tumor promoting mediators in IP-10-t...

Adipose-Derived Stem Cells (ASCs) for Tissue Engineering

P68: Combined Treatment of Spinal Cord Injury Using Transplantation of Motoneurons Derived Adipose Stem Cells and Adipose Mesenchymal Stem Cells Transfected with GDNF Following Valproic Acid Treatment

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Effect of progressive aerobic training, injection of adipose tissue-derived stem cells, and their combination on Bax and Bcl-2 levels of beta - pancreatic cells in diabetic rats

Introduction: Apoptosis is protective cellular process the plays an important role in the development and homeostasis of natural tissue as well as disease-causing factors. Current study was accomplished in order to determine the effect of progressive aerobic training with injection of adipose tissue-derived stem cells Bax (as an apoptotic protein) and Bcl-2 (as an anti-apoptotic protein) and th...

Differential gene expression by lithium chloride induction of adipose-derived stem cells into neural phenotype cells

Objective(s): Adipose-derived stem cells (ADSCs), with suitable and easy access, are multipotential cells that have the ability for differentiation into other mesodermal and transdifferentiate into neural phenotype cells. In this study, Lithium chloride (LiCl) was used for in vitro transdifferentiation of rat ADSCs into neuron-like cells (NLCs).<stro...

Comparative analysis of the Gene expression profile of Chemokine Receptors between Adipose-derived and Bone marrow-derived Mesenchymal Stem Cells

Introduction: Mesenchymal stem cells (MSCs) hold great promise in the field of regenerative medicine.Although originally isolated from bone marrow, MSCs have since been obtained from a variety of adult and neonatal tissues including the adipose tissue. Stemness and multipotential features of Mesenchymal Stem Cells (MSC) has been highlighted in many studies but there are many dark aspects in ex...